NeuroQuant Links Mold Illness to Structural Change in Brain

NeuroQuant Links Mold Illness to Structural Change in Brain

A common concern for those who are trying to understand cognitive problems in moldy patients is to answer how is it that inflammation in the body is inflammation in the brain. The blood brain barrier, as it is called, results from additional "tight junction features" between cells that line blood vessels. These tight junctions are loosened by particular inflammatory processes including TGF beta-1 and IL-1B. These two compounds are well shown to be significantly elevated in patients with systemic inflammatory response syndromes acquired following exposure to the interior environment of water-damaged buildings.

The computer program called NeuroQuant has been used in the traumatic brain injury field for some years. This unique and sophisticated program can take a properly run MRI of the brain and assess volumes of 15 different brain areas. To my knowledge, no one had used NQ to assess brain injury in patients with mold illness before.

Based on preliminary results; one of the "fathers of NQ" has shown a unique fingerprint of changes in white matter volume as well as injury to a gray matter structure, the caudate nucleus.

These preliminary data are being verified and expanded, but the longstanding tenuous argument against the link of exposure to water-damaged buildings leading to development of adverse cognitive effects appears to be ready to disappear under a blizzard of hard data. We are developing a before and after therapy protocol for such patients.

Below are several videos and information from the Virginia Institute of Neuropsychiatry:

You may visit their site for more information by clicking here.


  • Lisa
    - Apr 25, 2018
    Hi Mindy I was "diagnosed" approximately 15 years ago with Idiopathic Environmental Asthma. About the same time as I noticed that no matter how much time I spent outside, I could not get any kind of a tan. Not even the usual summer "flip flop tan". A detail I shared with every practitioner I met to see if they could answer the question of "why?". Fast forward to today... The first couple of weeks I was in detox heaven. The detox pain seemed minimal. I could actually breath at night. The utilization of my nebulizer, the rescue inhaler AND the combivent meds hourly usage had reduced to once every couple of days! I was slowly reducing the 3 other asthma medications I've been using to help keep me breathing. I was also enjoying my work a lot more. At about week two I started to feel a bit more pain, similar to being rundown by a Mac truck pulling a B-train. To help with the side affects I used laser therapy on the joints daily to help soften the blow. When I cut back on the cholestyramine, my breathing became laboured again. Therefore, I pushed through the pain - the lesser of two evils. But at week three, when my body was starting to detox a bit faster, I felt like I had been plummeled by a freight train during harvest season. The laser therapy was no longer keeping up with the pace. The pain was starting to affect my work. I have added extra magnesium to my daily routine, and it has helped bring the aches/pains back to a manageable degree. I also take antioxidants and a multi-mineral. I'm currently in week four. I've also added a 30 min infrared treatment to my daily activities. So far so good. I can finally see a light at the end of the tunnel. After 15 years of fighting to breath every day, I'm determined to remediate the detox pain through trial and error. I truly hope some of these ideas may help you as well Mindy.
    (reply to Lisa)
  • Joan
    - Feb 19, 2018
    Thanks for this helpful information. I have a lot of the symptoms but just became aware if the mold probles and results.
  • Mindy
    - Jan 21, 2018
    Did you take cholestyramine and, if so, did you have increased pain? I’m new to all this biotoxin stuff and I’m having crazy amounts of body aches and pain with this binder. I had to stop taking it. Any suggestions or ideas? I appreciate it. Thank you.
    (reply to Mindy)
  • Debi
    - Nov 20, 2014
    I'm going to be honest and say that your road back to health might not be easy, but I'm also here to say IT CAN BE DONE! You've already shown you're willing to fight for your health, and that tenaciousness (stubbornness, if you will), is going to get you the medical care you need and deserve. I struggled through 22 doctors (21 MDs, 1 ND) until I finally found a brilliant naturopath who took me seriously and was able to properly diagnose me. I later had to change to another (equally brilliant) ND, needing someone who specialized in chronic fatigue. He added Epstein Barr to my line-up (lucky me!) It's been 14 long, frustrating years of medical hell, but I can finally see the finish line, and it's a good feeling. You can do it, Jan-- keep at it. Same goes for Mary Ann and Mary. I wish you all the best!
    (reply to Debi)
  • Debi
    - Nov 20, 2014
    When I was 41, I thought I had full-blown Alzheimer's. Sometimes I had to look at my drivers license to remember my name! Suddenly, I could barely read or write, simple math -even while using a calculator- was out of the question. I would sit at my piano and cry, no longer able to figure out what the black things were on the pages, or how to move my hands along the keys, or at all, really. I spoke like a stroke victim; I couldn't form words or even remember them, and often garbled stuff would come out. The only words I could remember were swear words; I guess if there's a time a person needs to swear, it's when you've been exposed to mold! My exposure came from exercising in a public rec center, an old school (which should have been my first clue), which was kept very clean, but had massive long-term roof leaks and ancient air conditioners that spit out dirt, ice, anything but cold air. I found out later asthmatics could not be in that room without having instant attacks. We had always joked about the rec center employees smoking pot on their breaks because they were so slow and clueless, but now we know it was mold brain. OSHA would not do anything because I was "not an employee", even though I was proof of this being a hazardous building. The county-owned rec center did nothing, of course, and even "lost" my original report (lost it in the shredder, I'm sure). In 2001, there was no way I could find legal help. Or medical, for that matter. But 14 years later, I'm writing this (yay!) and getting closer to total health, which I will attain-- just watch me! The speech thing is better, but I still have problems getting words out or expressing my thoughts. And sadly, I just heard about another rec center employee who is obviously a victim of her sick working environment, not that it surprises me. I may try to somehow contact her. I'd love to see that place destroyed. After 20-some years of leaks, I think it's beyond remediation, and I pray to see justice served.
  • Jan
    - Oct 4, 2014
    I have found that I have difficulty remembering what things are called, trying to find the right words, forgetting what I just stood up to go do one get and I have to read slowly out loud to get anything from it. The most interesting part is the way I blend words. Frustration. After 2 1/2 yrs of living in and working in (same place) I moved to another place to find help as the Drs there were clueless. In the last month I have been diagnosed with Hypersensitivity Toxic Mold Syndrome and just yesterday (Friday) at closing my new dr calls and adds Myasthenia Gravis. Still waiting a couple more tests from Lung Biopsy....and some more labs. Lost totally lost but at least they don't look at me like I'm crazy where I moved to. Still fighting the company that I worked for that caused these issues.
  • mary ann
    - May 28, 2014
    I am so relieved to find someone else with the same speech problem. I say things that I didn't intend to say and that really don't reflect my thinking. It seems as though I can't think quick enough so my brain just pops something out. Right now I'm having a hard time expressing the experience. I already moved away from a very moldy house and this problem comes and goes whenever I'm exposed to moldy weather or moldy places where I work. I hope we both find relief
    (reply to mary ann)
  • Mary
    - Feb 7, 2014
    Just want to say I'm glad to have read this stuff. I am having a difficult time with my speech. One dr. suggested it to be sinus drainage. They don't have a clue. I feel like a stroke victim. I think one thing and say another.

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